Merkel Cell Carcinoma

A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245)

Also Known As:

Carcinoma, Merkel Cell; Merkel Cell Cancer; Merkle Tumors; Cancer, Merkel Cell; Cell Cancer, Merkel; Tumor, Merkel Cell; Tumors, Merkle; Merkel Cell Tumor

Infections: 526564
- Virus Diseases: 41777
  - DNA Virus Infections: 139
    - Polyomavirus Infections: 84
      - Merkel Cell Carcinoma: 1156
  - Tumor Virus Infections: 39
    - Merkel Cell Carcinoma: 1156
Neoplasms: 1324753
- Neoplasms by Histologic Type: 2
  - Germ Cell and Embryonal Neoplasms: 4454
    - Neuroectodermal Tumors: 217
      - Neuroendocrine Tumors: 6270
        Neuroendocrine Carcinoma: 1123
        Merkel Cell Carcinoma: 1156
  - Glandular and Epithelial Neoplasms: 439
    - Carcinoma: 141855
      - Adenocarcinoma: 58365
        Neuroendocrine Carcinoma: 1123
        Merkel Cell Carcinoma: 1156
  - Nerve Tissue Neoplasms: 1
    - Neuroectodermal Tumors: 217
      - Neuroendocrine Tumors: 6270
        Neuroendocrine Carcinoma: 1123
        Merkel Cell Carcinoma: 1156

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